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顾杰(硕导)

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个人简介

姓名:顾杰

性别:男

出生年月:198211

职称:副研究员

E-mail: 1000004531@ujs.edu.cn

学术简历

学习经历:

2001/09-2005/06,扬州大学,生物科学与技术,学士学位

2005/09-2008/06,扬州大学,生物化学与分子生物学,硕士学位

2009/03-2011/02,香港浸会大学,生物学,硕士学位

2011/07-2014/06,香港浸会大学,生物学,博士学位

工作经历:

2014/07-2015/06,香港浸会大学,生物系,助理研究员

2015/06-2016/08,江苏大学,生命科学研究院,助理研究员

2017/09-至今,江苏大学,生命科学研究院,副研究员

研究兴趣

重金属的分子毒理机制

钙离子稳态失衡相关疾病

环境污染与临床疾病相关研究

科研项目

国家自然科学基金青年基金,31600952,钙离子敏感受体CaSR的激活可减轻镉对肾小管上皮细胞的毒性的分子机理的研究,2017/01-2019/1220万,在研,主持

香港General Research Fund项目,GRF 261610、 “The Identification of Stanniocalcin-1 Target Cells and the Characterization of the In-Situ Ca2+-Sensing and Transport Mechanisms in Gill Epithelial Cells of Japanese Eels”, 2010-2013HK$986,000,已结题,参与

【近年发表的论文】

(1). Gu J, Li JW, Tse KF, Chan TF, Wong CK*. Transcriptomic responses of CS gland of Japanese eels (Anguilla japonica) to Changes in Water Salinity. Sci Rep. 2015, 5: 9836.

(2). Gu J, Law AY, Yeung BH, Wong CK*. Characterization of stanniocalcin 1 binding and signaling in gill cells of Japanese eels. J Mol Endocrinol. 2015, 54(3):305-314.

(3). Gu J, Law AY, Yeung BH, Wong CK*. Activation of gill Ca2+-sensing receptor as a protective pathway to reduce Ca2+-induced cytotoxicity. 2014, J Mol Endocrinol. 53(2):155-64.

(4). Gu J, Chan LS, Wong CK, Wong NS, Wong CK, Leung KN, Mak NK*. Effect of benzo[a]pyrene on the production of vascular endothelial growth factor by human eosinophilic leukemia EoL-1 cells. J Environ Pathol Toxicol Oncol. 2011, 30(3):241-249.

(5). Lai KP, Li JW, Gu J, Chan TF, Tse WK, Wong CK. Transcriptomic analysis reveals specific osmoregulatory adaptive responses in gill mitochondria-rich cells and pavement cells of the Japanese eel. BMC Genomics. 2015, 16:1072.

(6). Tse WK, Sun J, Zhang H, Lai KP, Gu J, Sheung Law AY, Yee Yeung BH, Ching Chow S, Qiu JW, Wong CK*. Data for transcriptomic and iTRAQ proteomic analysis of Anguilla japonica gills in response to osmotic stress. Data Brief. 2015, 3:120-125.

(7). Tse WK, Sun J, Zhang H, Lai KP, Gu J, Qiu JW, Wong CK. iTRAQ-based quantitative proteomic analysis reveals acute hypo-osmotic responsive proteins in the gills of the Japanese eel (Anguilla japonica). J Proteomics. 2014, 105:133-143.


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