马毅，男，甘肃庆阳人，博士研究生

Email: yima@ujs.edu.cn

地址：江苏省镇江市学府路301号，江苏大学，生命科学学院

邮编：212013

【教育经历】

2023.08--至今 江苏大学，生命科学学院，教师

2022.05--2023.05 澳大利亚墨尔本大学科学学院，动物营养与饲料科学，博士联合培养

2019.09--2023.06 扬州大学动物科学与技术学院，动物营养与饲料科学，博士学位

2017.09--2019.06 石河子大学动物科学与技术学院，动物营养与饲料科学，硕士学位

2013.09--2017.06 石河子大学动物科学与技术学院，动物科学，学士学位

【研究方向】

1.肠道微生物与机体免疫的互作效应研究

2.生物钟对机体免疫及代谢功能的调控研究

3.工程菌的改造及应用

4.反刍动物瘤胃酸中毒的发生机制与调控研究

【社会服务】

担任Animal、Journal of Dairy Research、Nutrients及Frontiers in Veterinary Science国际期刊（SCI）审稿人。

【发表论文】

1. Ma, Yi., Wang, C., Elmhadi, M., Zhang, H., Han, Y., Shen, B., and Wang, H. R. Thiamine ameliorates metabolic disorders induced by a long-term high-concentrate diet and promotes rumen epithelial development in goats. Journal of Dairy Science, 2021, 104(11), 11522-11536.

2. Ma, Yi., Wang, C., Elmhadi, M., Zhang, H., Liu, F., Gao, X., and Wang, H. R. Dietary supplementation of thiamine enhances colonic integrity and modulates mucosal inflammation injury in goats challenged by lipopolysaccharide and low pH. British Journal of Nutrition, 2022, 128(11), 2147-2157.

3. Ma, Yi., Elmhadi, M., Wang, C., Li, Z., Zhang, H., He, B., and Wang, H. R. Thiamine Supplementation Alleviates Lipopolysaccharide-Triggered Adaptive Inflammatory Response and Modulates Energy State via Suppression of NFκB/p38 MAPK/AMPK Signaling in Rumen Epithelial Cells of Goats. Antioxidants, 2022, 11(10), 2048.

4. Ma, Yi., Wang, C., Zhang, H., Yu, L., Dong, L., Gong, D., and Wang, H. Illumina sequencing and metabolomics analysis reveal thiamine modulation of ruminal microbiota and metabolome characteristics in goats fed a high-concentrate diet. Frontiers in Microbiology, 2021, 12, 653283.

5. Ma, Yi., Elmhadi, M., Wang, C., Zhang, H., and Wang, H. R. Dietary supplementation of thiamine down-regulates the expression of mitophagy and endoplasmic reticulum stress-related genes in the rumen epithelium of goats during high-concentrate diet feeding. Italian Journal of Animal Science, 2021, 20(1), 2220-2231.

6. Zhang, H., Ma, Yi., Wang, M., Elsabagh, M., Loor, J. J., & Wang, H. Dietary supplementation of l-arginine and N-carbamylglutamate enhances duodenal barrier and mitochondrial functions and suppresses duodenal inflammation and mitophagy in suckling lambs suffering from intrauterine-growth-restriction. Food & Function, 2020, 11(5), 4456-4470.

7. Zhang, H., Yan, A., Liu, X., Ma, Yi., Zhao, F., Wang, M., and Wang, H. R. Melatonin ameliorates ochratoxin A induced liver inflammation, oxidative stress and mitophagy in mice involving in intestinal microbiota and restoring the intestinal barrier function. Journal of Hazardous Materials, 2021, 407, 124489.

8. Zhang, H., Liu, X., Elsabagh, M., Zhang, Y., Ma, Yi., and Jiang, H. Effects of the Gut Microbiota and Barrier Function on Melatonin Efficacy in Alleviating Liver Injury. Antioxidants, 2022, 11(9), 1727.

9. Wang, J., Cheng, L., Chaudhry, A. S., Khanaki, H., Abbasi, I. H., Ma, Yi., and Zhang, S. Silage Mixtures of Alfalfa with Sweet Sorghum Alter Blood and Rumen Physiological Status and Rumen Microbiota of Karakul Lambs. Animals, 2022, 12(19), 2591.

10. Zhang, H., Zheng, Y., Liu, X., Zha, X., Elsabagh, M., Ma, Yi., and Wang, M. Autophagy attenuates placental apoptosis, oxidative stress and fetal growth restriction in pregnant ewes. Environment International, 2023, 173, 107806.

11. Sun, H., Zhao, F., Hou, F., Zhang, X., Ma, Yi., and Wang, H. Influences of naringin supplementation on ruminal fermentation, inflammatory response, antioxidant capacity and bacterial community in high-concentrate diet of fattening goats. Italian Journal of Animal Science, 2022, 21(1), 1498-1507.

12. Zhang, H., Zheng, Y., Zha, X., Liu, X., Ma, Yi., Loor, J. J., and Jiang, H. Dietary N-carbamylglutamate and L-arginine supplementation improves redox status and suppresses apoptosis in the colon of intrauterine growth-retarded suckling lambs. Animal Nutrition, 2022, 11, 359-368.

13. Zhang, H., Zheng, Y., Zha, X., Ma, Yi., Liu, X., Elsabagh, M., & Wang, M. (2022). Dietary L-Arginine or N-Carbamylglutamate Alleviates Colonic Barrier Injury, Oxidative Stress, and Inflammation by Modulation of Intestinal Microbiota in Intrauterine Growth-Retarded Suckling Lambs. Antioxidants, 11(11), 2251.

【参与项目】

2022年，扬州大学研究生国际合作交流基金

2021年，扬州大学优秀博士论文基金

2019年，基于CCpA蛋白调控山羊瘤胃牛链球菌对乳酸代谢的分子机制（31872988，参与）；

2019年，反刍动物瘤胃中乳酸生成和代谢机制及其与瘤胃酸中毒的关系（31572429，参与）