
马毅,博士,硕士生导师
邮箱: yima@ujs.edu.cn
地址:江苏省镇江市学府路301号,江苏大学,生物科学与技术学院(微生物团队)
邮编:212013
【教育及工作经历】
2023.08--至今 江苏大学,微生物学(合成生物学领域),教师
2019.09--2023.06 扬州大学/墨尔本大学(澳大利亚),动物营养学,联合培养博士
2017.09--2019.06 石河子大学,动物营养学,硕士
2013.09--2017.06 石河子大学,动物科学,学士
【研究方向】
1. 代谢工程(合成生物学)助力动物健康养殖
2. 酶工程(合成生物学)促进动物饲料高效利用
【社会服务】
担任Frontiers in immunology客座编辑; Biotechnology Advances、Animal、Journal of Dairy Scicence 、Journal of Dairy Research、Frontiers等SCI期刊审稿人。
【承担及参与项目】
1.《硫胺素对 SARA 山羊乳腺炎症的调控功能及机制研究》(江苏省青年基金:BK20240840),省拨20万,2024.09~2027.08,在研;
2.《工程化植物乳杆菌L-赖氨酸代谢途径的构建及其在肉羊肠道内源性合成的研究》(高校联合基金,HLFD202502),10万,2024.05~2027.05,在研;
3. 《L-赖氨酸代谢途径的优化及转录调控遗传元件开发》(省部级联合项目),13万,2026.05~2029.05,在研;
4.《秸秆废碳高效转化生物饲料关键技术研究及应用》(镇江市科技项目:CN2024001),市拨15万,2024.09~2027.08,在研。
5. 《农业废弃碳源高效转化蛋白饲料关键技术集成及产业化》(省重点研发项目:BE2023399),省拨500万,2023.04~2027.03,在研。
【主要代表性论著;H-index= 13,总引用>500】
1. Xu, J., Chen, X., Ma, Yi., Ren, J., Xu, G., Zhang, P., & Wu, S. Rumen Mycobiome Thiamine Metabolism Contributes to Subacute Rumen Acidosis Tolerance in Goats Through Enhancing Epithelial Cell Proliferation via IGFBP2/IGF1 Axis Activation. Exploration, 2026, 70142.(共同一作,中科院一区,IF=22.5);
2. Ma, Yi., Zhang, J., Chen, C., Wang, M., Li, H., Deng, Y., & Guo, Z. Thiamine ameliorates subacute ruminal acidosis–induced mastitis in goats and is associated with modulation of the NF-κB/NLRP3/CLOCK axis and rumen microbial homeostasis. Journal of Dairy Science, 2026,5:5112-5129.(第一作者,中科院一区,IF=4.4);
3. Ma, Yi., Gao, X., Elsabagh, M., Feng, Y., Chen, Y., Cheng, L., & Liu, F. (2025). Anti-Inflammatory potential of lactic acid bacteria for dairy cows during the periparturient period. Animal Feed Science and Technology, 321, 116234.(第一作者,中科院二区,IF=2.7);
4. Ma, Yi., Yang, P., Li, P., Elsabagh, M., Cheng, L., Chen, H., and Xu, M. Dietary thiamine supplementation modulates ruminal microbiota and partly restores lactation performance in lactating Hu ewes under heat-stress conditions. Animal Feed Science and Technology, 2024, 318, 116119.(第一作者,中科院二区,IF=2.7);
5. Ma, Yi., Cheng, L., Gao, X., Elsabagh, M., Feng, Y., Li, Z., and Liu, F. Melatonin modulates lipopolysaccharides-induced inflammatory response and maintains circadian rhythm associated with histone H3 acetylation in bovine mammary epithelial cells. Journal of Functional Foods, 2024, 116, 106156.(第一作者,中科院二区Top,IF=5.6);
6. Ma, Yi., Wang, C., Elmhadi, M., Zhang, H., Liu, F., Gao, X., and Wang, H. R. Dietary supplementation of thiamine enhances colonic integrity and modulates mucosal inflammation injury in goats challenged by lipopolysaccharide and low pH. British Journal of Nutrition, 2022, 128(11), 2147-2157. (第一作者,中科院三区,IF=4.125);
7. Ma, Yi., Elmhadi, M., Wang, C., Li, Z., Zhang, H., He, B., and Wang, H. R. Thiamine Supplementation Alleviates Lipopolysaccharide-Triggered Adaptive Inflammatory Response and Modulates Energy State via Suppression of NFκB/p38 MAPK/AMPK Signaling in Rumen Epithelial Cells of Goats. Antioxidants, 2022, 11(10), 2048. (第一作者,中科院二区Top,IF=7.675);
8. Ma, Yi., Wang, C., Elmhadi, M., Zhang, H., Han, Y., Shen, B., and Wang, H. R. Thiamine ameliorates metabolic disorders induced by a long-term high-concentrate diet and promotes rumen epithelial development in goats. Journal of Dairy Science, 2021, 104(11), 11522-11536.(第一作者,中科院一区,IF=4.4);
9. Ma, Yi., Wang, C., Zhang, H., Yu, L., Dong, L., Gong, D., and Wang, H. Illumina sequencing and metabolomics analysis reveal thiamine modulation of ruminal microbiota and metabolome characteristics in goats fed a high-concentrate diet. Frontiers in Microbiology, 2021, 12, 653283. (第一作者,中科院一区,IF=6.064);
10. Ma, Yi., Elmhadi, M., Wang, C., Zhang, H., and Wang, H. R. Dietary supplementation of thiamine down-regulates the expression of mitophagy and endoplasmic reticulum stress-related genes in the rumen epithelium of goats during high-concentrate diet feeding. Italian Journal of Animal Science, 2021, 20(1), 2220-2231. (第一作者,中科院三区,IF=2.552)
11. Zhang, H., Ma, Yi., Wang, M., Elsabagh, M., Loor, J. J., & Wang, H. Dietary supplementation of l-arginine and N-carbamylglutamate enhances duodenal barrier and mitochondrial functions and suppresses duodenal inflammation and mitophagy in suckling lambs suffering from intrauterine-growth-restriction. Food & Function, 2020, 11(5), 4456-4470.(第二作者,中科院一区,IF=6.317)
12. Zhang, H., Yan, A., Liu, X., Ma, Yi., Zhao, F., Wang, M., and Wang, H. R. Melatonin ameliorates ochratoxin A induced liver inflammation, oxidative stress and mitophagy in mice involving in intestinal microbiota and restoring the intestinal barrier function. Journal of Hazardous Materials, 2021, 407, 124489. (第四作者,中科院一区,IF=14.224)