【个人简介】 姓名：邱立鹏 性别：女 职称：副研究员 电话：0511—88791702 传真：0511—88791923 E-mail：qiulp@ujs.edu.cn 【学习经历】 2007.08—2011.07 中国科学院微生物研究所，生物化学与分子生物学专业，理学博士 2001.08—2004.07 沈阳药科大学制药工程学院，微生物与生化药学专业，理学硕士 2001-2002 沈阳药科大学，完成课程学习 2002-2004 浙江大学药学院，完成硕士论文 1997.08—2001.07 沈阳药科大学制药工程学院，微生物制药专业，工学学士 【工作经历】 2011.07—现在 江苏大学生命科学研究院，助理研究员/副研究员 2013.12—2016.09 美国约翰霍普金斯大学医学院，访问学者/博士后 2011.09—2016.06 江苏大学食品科学与工程博士后流动站，博士后，已出站 2004.07—2007.07 常州大学化学工程学院制药工程教研室，助教 【研究领域】 非编码RNA在肝癌和肺癌中的功能及机制研究 【科研项目】 主持项目 1. 国家自然科学基金青年基金（81402840），2015.01-2017.12，结题 2. 江苏省自然科学基金（BK20130495），2013.07-2016.06，结题 3. 中国博士后科学基金面上项目（2012M511206），2012.09-2014.09，结题 4. 江苏大学高级专业人才科研启动基金（11JDG120），2012.01-2014.12，在研 5. 江苏大学青年骨干教师培养工程资助， 2015.01-2018.12，在研 参加项目 1. 国家自然科学基金青年基金（31402016），2015.01-2017.12，结题，主要参与人（3/5） 2. 国家自然科学基金（30970146），2010.01-2012.12，结题 3. 国家973计划（2007CB512800）子课题，2007.01-2011.12，结题 4. 国家863计划（2006AA02A241），2007.01-2010.12，结题 【科研成果】 已发表SCI收录论文二十余篇，共计引用次数550余次。 1. Lipeng Qiu, Han Xu, Mengchen Ji, Dongsheng Shang, Ziwen Lu, Yihang Wu, Zhigang Tu, Hanqing Liu*. Circular RNAs in hepatocellular carcinoma: biomarkers, functions and mechanisms. Life Sci. 2019,231:116660.(IF=3.448) 2. Lipeng Qiu*, Tao Wang, Qi Ge, Han Xu, Yihang Wu, Qi Tang, Keping Chen*. Circular RNA signature in hepatocellular carcinoma. J Cancer. 2019, 10(15): 3361-3372. (IF=3.249, 引用次数：1) 3. Lipeng Qiu#, Yan Zhang#, Danh C. Do, Xia Ke, Simin Zhang, Kristin Lambert, Shruthi Kumar, Chengping Hu, Yufeng Zhou, Faoud T. Ishmael* and Peisong Gao*. miR-155 modulates cockroach allergen- and oxidative stress-induced cyclooxygenase-2 in asthma. J Immunol. 2018, 201(3): 916-929. (IF=4.569，引用次数：5) 4. Lipeng Qiu*, Tao Wang, Qi Tang, Guohui Li, Peng Wu and Keping Chen*. Long non-coding RNAs: regulators of viral infection and the interferon antiviral response. Front Microbiol. 2018. 9: 1621.(IF=4.019，引用次数：5) 5. Lipeng Qiu*, Yihang Wu, Xiaofeng Yu, Qi Tang, Liang Chen, Keping Chen*. The emerging role of circular RNAs in hepatocellular carcinoma. J Cancer. 2018, 9(9): 1548-1559. (IF=3.249，引用次数：19) 6. Lipeng Qiu*, Tao Wang, Xiuquan Xu, Yihang Wu, Qi Tang and Keping Chen*. Long non-coding RNAs in hepatitis B virus-related hepatocellular carcinoma: regulation, functions and underlying mechanisms. Int. J. Mol. Sci. 2017, 18(12): 2505. (IF=3.687，引用次数：5) 7. Lipeng Qiu, Qi Tang, Guohui Li, Keping Chen*.Long non-coding RNAs as biomarkers and therapeutic targets: Recent insights into hepatocellular carcinoma. Life Sci. 2017, 191:273-282. (IF=3.448，引用次数：39) 8. Li-Peng Qiu, Liang Chen, Ke-Ping Chen*. Antihepatitis B therapy: a review of current medications and novel small molecule inhibitors. Fundam Clin Pharmacol. 2014, 28(4): 364-381. (IF=2.349，引用次数：14) 9. Li-Peng Qiu, Ke-Ping Chen*. Anti-HBV agents derived from botanical origin. Fitoterapia. 2013, 84: 140-157. (IF=2.642，引用次数：29) 10. Lipeng Qiu, Hongxia Fan, Wensong Jin, Bao Zhao, Yanzhong Wang, Ying Ju, Lizhao Chen, Yu Chen, Zhongping Duan and Songdong Meng*. MiR-122-induced down-regulation of HO-1 negatively affects miR-122-mediated suppression of HBV. Biochem Biophys Res Commun. 2010, 398 (4): 771-777. (IF=2.559，引用次数：111) 11. Saifeng Wang#, Lipeng Qiu#, Xiaoli Yan, Wensong Jin, Yanzhong Wang, Lizhao Chen, Erjie Wu, Xin Ye, George F Gao, Fusheng Wang, Yu Chen, Zhongping Duan*, Songdong Meng*. Loss of microRNA 122 expression in patients with hepatitis B enhances hepatitis B virus replication through cyclin G1-modulated P53 activity. Hepatology. 2012,55(3): 730-741. (共同第一作者, IF=14.079，引用次数：172) 12. Saifeng Wang#, Lipeng Qiu#, Guangze Liu, Yang Li, Xiaojun Zhang, Wensong Jin, George F Gao, Xianping Kong*, Songdong Meng*. Heat shock protein gp96 enhances humoral and T cell responses, decreases Treg frequency and potentiates the anti-HBV activity in BALB/c and transgenic mice. Vaccine. 2011, 29(37): 6342-6351. (共同第一作者, IF=3.285，引用次数：25) 13. Lipeng Qiu*, Qi Tang, Guohui Li. Heme oxygenase 1 attenuates cockroach allergen-induced airway inflammation. J Allergy Clin Immunol, 2018,141(2), Supp, AB117. Annual meeting of AAAAI (the American Academy of Allergy, Asthma & Immunology). Orlando. March, 2018.(IF=13.258, 会议论文) 14. Lipeng Qiu, Yufeng Zhou, Yilin Zhao, Danh Do, Heng Wang, Changjun Li, Xiaopeng Liu, Xu Cao, Mei Wan, Peisong Gao*. microRNA-155 regulates cockroach allergen induced cyclooxygenase-2 expression in airway epithelium. J Allergy Clin Immunol. 2016, 137(2), Supp, AB175. Annual meeting of AAAAI. Los angeles. March, 2016. (IF=13.258, 会议论文) 15. Zhicong Zhao, Dongsheng Shang, Lipeng Qiu, Chang Guo, Yanyan Li, Hanqing Liu, Guoyue Yuan*, Zhigang Tu*.4,5-diphenyl-2-methyl picolinate induces cellular senescence by accumulating DNA damage and activating associated signaling pathways in gastric cancer. Life Sci. 2019, 238:116973. (IF=3.448) 16. Shengjie Chen, Tianyi Gu, Ziwen Lu, Lipeng Qiu, Guoliang Xiao, Xiaozhong Zhu, Feng Li, Hui Yu, Gang Li, Hanqing Liu*. Roles of MYC-targeting long non-coding RNA MINCR in cell cycle regulation and apoptosis in non-small cell lung Cancer. Resp Res. 2019, 20: 202. (IF=3.829) 17. Qi Tang, Lipeng Qiu, Guohui Li*. Baculovirus-encoded microRNAs: a brief overview and future prospects. Curr Microbiol. 2019, 76: 738-743. (IF=1.373，引用次数：2) 18. Liang Chen, Yanhua Yang, Yiting Wang, Lipeng Qiu, Hengchuan Xia, Aiai Wang, Hailong Liu, Hongfei Shi*, Keping Chen*. Proteomic response of the rat liver in differential swimming modes. Clin Exp Pharmacol P. 2018, 45(6): 581-590. (IF=2.092) 19. Huan Zuo, Liang Chen, Ming Kong, Yanhua Yang, Peng Lv, Lipeng Qiu, Qiang Wang, Shangshang Ma, Keping Chen*. The toxic effect of sodium fluoride on Spodoptera frugiperda 9 cells and differential proteinanalysis following NaF treatment of cells. Environ Pollut. 2018, 236: 313-323. (IF=4.358，引用次数：1) 20. Huan Zuo, Liang Chen, Ming Kong, Lipeng Qiu, Peng Lv, Peng Wu, Yanhua Yang, Keping Chen*. Toxic effects of fluoride on organisms. Life Sci. 2018, 198: 18-24. (IF=3.234，引用次数：22) 21. Yufeng Zhou, Dan C.Do, Faoud T. Ishmael, Mario Leonardo Squadrito, Ho Man Tang, Ho Lam Tang, Man-Hsun Hsu, Lipeng Qiu, Changjun Li, Yongqing Zhang, Kevin G. Becker, Mei Wan, Shau-Ku Huang*, Peisong Gao*.Mannose receptor modulates macrophage polarization and allergic inflammation through miR-511-3p. J Allergy Clin Immunol, 2018, 141(1): 350-364. (IF=13.258，引用次数：13) 22. Yi-Hang Wu*, Bing-Yi Zhang, Li-Peng Qiu, Rong-Fa Guan, Zi-Hong Ye, Xiao-Ping Yu. Structure properties and mechanisms of action of naturally originated phenolic acids and their derivatives against human viral infections. Curr Med Chem. 2017, 24(38): 4279-4302. (IF=3.455，引用次数：1) 23. Qi Tang, Peng Wu, Zhaoyang Hu, Yanhua Yang, Lipeng Qiu, Hanqing Liu, Shanying Zhu, Zhongjian Guo, Hengchuan Xia, Keping Chen*, Guohui Li*. Evidence for the role of BmNPV Bm65 protein in the repair of ultraviolet-induced DNA damage. J Invertebr Pathol. 2017, 149: 82-86. (IF=2.379，引用次数：3) 24. Guohui Li, Qian Zhou, Lipeng Qiu, Qin Yao, Keping Chen, Qi Tang*, Zhaoyang Hu*. Serine protease Bm-SP142 was differentially expressed in resistant and susceptible Bombyx mori strains, involving in the defence response to viral infection. PLoS ONE. 2017, 12(4): e0175518. (IF=2.766，引用次数：4) 25. Feng li, Yi-Dan Mao, Yi-Fan Wang, Aun Raza, Li-Peng Qiu and Xiu-Quan Xu*. Optimization of Untrasonic-Assisted Enzymatic Extraction Conditions for Improving Total Phenolic Content, Antioxidant and Antitumor Activities In Vitro from Trapa quadrispinosa Roxb. Residues. Molecules. 2017, 22(3): 396.(IF=3.098) 26. Yilin Zhao, Xiaoyan Luo, Lipeng Qiu, Danh C. Do, Xia Ke, Eric Zaccone, Bradley J. Undem, Peisong Gao*, Aryl Hydrocarbon receptor in airway epithelium exacerbates cockroach allergen-induced asthma through autophagy, J Allergy Clin Immunol, 2017, 139(2), Supp, AB268. Annual meeting of AAAAI. Atlanta. March, 2017. (IF=13.258, 会议论文) 27. Weiwei Liu, Mi Chen, Xinghui Li, Bao Zhao, Junwei Hou, Huaguo Zheng, Lipeng Qiu, Zihai Li, Songdong Meng*. Interaction of Toll-Like Receptors with the Molecular Chaperone Gp96 Is Essential for Its Activation of Cytotoxic T Lymphocyte Response. PLoS ONE. 2016, 11(5): e0155202. (IF=2.766，引用次数：6) 28. Yilin Zhao, Lipeng Qiu, Danh Do, Heng Wang, Xiaopeng Liu, Peisong Gao. MicroRNA-203 regulates aryl hydrocarbon receptor in cockroach mediated allergic responses. J Allergy Clin Immunol. 2016, 137(2), Supp, AB199. Annual meeting of AAAAI. Los angeles. March, 2016. (IF=13.258, 会议论文) 29. Ting Xu#, Yufeng Zhou#, Lipeng Qiu, Danh C. Do, Yilin Zhao, Zhuang Cui, Heng Wang, Xiaopeng Liu, Arjun Saradna, Mei Wan, and Peisong Gao*. Aryl hydrocarbon receptor protects lungs from cockroach allergen-induced inflammation by modulating mesenchymal stem cells. J Immunol. 2015, 195(12):5539-5550. (IF=4.569，引用次数：16) 30. Qi Tang, Zhaoyang Hu, Yanhua Yang, Huiling Wu, Lipeng Qiu, Keping Chen*, Guohui Li*. Overexpression of Bm65 correlates with reduced susceptibility to inactivation by UV light. J Invertebr Pathol. 2015, 127:87-92. (IF=2.379，引用次数：7) 31. Yu Zhang, Yulin Ren, Yan Wu, Bao Zhao, Lipeng Qiu, Xiaodong Li, Dongping Xu, Jun Liu, George F. Gao*, Songdong Meng*. The L60V variation in HBV core protein elicits new epitope-specific cytotoxic T lymphocytes and enhances viral replication. J Virol. 2013, 87(14): 8075-8084. (IF=4.368，引用次数：13) 32. Zhen Liu#, Xinghui Li#, Lipeng Qiu, Xiaojun Zhang, Lizhao Chen, Sheng Cao, Fusheng Wang and Songdong Meng*. Treg suppress CTL responses upon immunization with HSP gp96. Eur J Immunol. 2009, 39(11): 3110-3120. (IF=4.248，引用次数：49) 33. 郜衍周, 范红霞，邱立鹏*，孟颂东*. IFN-α对gp96的上调降低其抗HBV的效率. 微生物学报. 2013, 53(8): 867-874. 34. 任玉林，张宇，邱立鹏，张小俊，陈煜，王福生，谢尧，高斌，段钟平，孟颂东*. 新型HLA-A2限制的B, C型HBV特异性CTL表位的筛选及鉴定. 科学通报. 2010,55(30): 2915-2924. 35. 于荣敏*，邱立鹏，赵昱，孙平华，叶文才，姚新生. 植物生物转化技术在药用活性成分生产及新药开发中的应用. 中国新药杂志. 2005,14(4): 407-412. 【在读硕、博士人数】 2 【已毕业硕、博士人数】 0 |
