YongZhong Hou，PhD, Professor.
Research focus：
PPARs (PPARα, PPARγ, PPARδ) functions and role on cancer cell proliferation, metabolism, autophagy, and immune escape.
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Selected Publications
1. Zhou D, Jin J, Liu Q, Shi J, Hou Y*. PPARδ agonist enhances colitis-associated colorectal cancer. Eur J Pharmacol. 2019;842:248-254.
2.You M, Gao J, Jin J, Hou Y*. PPARα Enhances Cancer Cell Chemotherapy Sensitivity by Autophagy Induction. J Oncol. 2018 Nov 4;2018:6458537.
3. Zhang W, Xu Y, Xu Q, Shi H, Shi J*, Hou Y*. PPARδ promotes tumor progression via activation of Glut1 and SLC1-A5 transcription. Carcinogenesis. 2017;38(7):748-755.
4. You M, Jin J, Liu Q, Xu Q, Shi J*, Hou Y*. PPARα Promotes Cancer Cell Glut1Transcription Repression. J Cell Biochem. 2017,118(6):1556-1562.
5. Zhang R, Jin J, Shi J*, Hou Y*. INGs are potential drug targets for cancer. J Cancer Res Clin Oncol. 2017;143:189-197.
6.Xu Y, Jin J, Zhang Z, Zhang W, Gao J, Liu Q, Zhou C, Shi H, Hou Y*, Shi J*. EGFR/MDM2 signaling promotes NFkB activation via PPARγ degradation. Carcinogenesis, 2016;37:215-22.
7. Xu H, You M, Shi H, Hou Y*. Ubiquitin-mediated NFκB degradation pathway.Cell Mol Immunol. 2015;12:653-5
8. You M, Yuan S, Shi J, Hou Y*. PPARδ signaling regulates colorectal cancer. Current Pharmaceutical Design. 2015; 21(21):2956-9
9. Hou Y*, Zhang Z, Xu Q, Wang H, Xu Y, Chen K. ING4 induces NFκB/p65 ubiquitin-dependent degradation. Oncogene. 2014, 33:1997-2003.
10. Hou Y*, Gao J, Xu H, Xu Y, Zhang Z, Xu Q, Zhang C. PPARγ E3 ubiquitin ligase regulates MUC1-C oncoprotein stability. Oncogene. 2014, 33:5619-25.
11. Hou Y, France M, Chadee K*. PPARγ functions as E3 ubiquitin ligase to terminate NFкB activation. Nature Communications. 2012, 3:1300.
Position available:
Professor and associated professor positions are available in cancer biology. We offer competative salaries and excellent benefits. Please view the link https://main.v.ujs.edu.cn/info/1093/20846.htm. Interested applicants may email a copy of their resume to: houyz@ujs.edu.cn.
