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December 7, 2023
YongZhong Hou


YongZhong Hou,PhD, Professor.

Research focus
PPARs (PPARα, PPARγ, PPARδ) functions and role on cancer cell proliferation, metabolism, autophagy, and immune escape.
Selected Publications
1. Zhou D, Jin J, Liu Q, Shi J, Hou Y*. PPARδ agonist enhances colitis-associated colorectal cancer. Eur J Pharmacol. 2019;842:248-254.
2.You M, Gao J, Jin J, Hou Y*. PPARα Enhances Cancer Cell Chemotherapy Sensitivity by Autophagy Induction. J Oncol. 2018 Nov 4;2018:6458537.
3. Zhang W, Xu Y, Xu Q, Shi H, Shi J*, Hou Y*. PPARδ promotes tumor progression via activation of Glut1   and SLC1-A5 transcription. Carcinogenesis. 2017;38(7):748-755.
4. You M, Jin J, Liu Q, Xu Q, Shi J*, Hou Y*. PPARα Promotes Cancer Cell Glut1Transcription Repression. J Cell Biochem. 2017,118(6):1556-1562.
5. Zhang R, Jin J, Shi J*, Hou Y*. INGs are potential drug targets for cancer. J Cancer Res Clin  Oncol. 2017;143:189-197.
6.Xu Y, Jin J, Zhang Z, Zhang W, Gao J, Liu Q, Zhou C, Shi H, Hou Y*, Shi J*. EGFR/MDM2 signaling promotes NFkB activation via PPARγ degradation. Carcinogenesis, 2016;37:215-22.
7. Xu H, You M, Shi H,  Hou Y*. Ubiquitin-mediated NFκB degradation pathway.Cell Mol Immunol. 2015;12:653-5
8. You M, Yuan S, Shi J, Hou Y*. PPARδ signaling regulates colorectal cancer. Current Pharmaceutical Design. 2015; 21(21):2956-9
9. Hou Y*, Zhang Z, Xu Q, Wang H, Xu Y, Chen K. ING4 induces NFκB/p65 ubiquitin-dependent degradation. Oncogene. 2014, 33:1997-2003.
10. Hou Y*, Gao J, Xu H, Xu Y, Zhang Z, Xu Q, Zhang C. PPARγ E3 ubiquitin ligase regulates MUC1-C oncoprotein stability. Oncogene. 2014, 33:5619-25.
11. Hou Y, France M, Chadee K*. PPARγ functions as E3 ubiquitin ligase to terminate NFкB activation. Nature Communications. 2012, 3:1300.


Position available:

Professor and associated professor positions are available in cancer biology. We offer competative salaries and excellent benefits. Please view the link https://main.v.ujs.edu.cn/info/1093/20846.htm. Interested applicants may email a copy of their resume to: houyz@ujs.edu.cn.