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December 4, 2019
Lu Jian

 Curriculum Vitae


Jian Lu , PhD                

Research  Associate
Institute of Life Sciences, Jiangsu University301 Xuefu Road,Zhenjiang,Jiangsu Province,212013,P.R.CHINA

Research objectives
1.Reveal the effects of environmental toxin on the physiology
biochemistry metabolismdevelopment and genetics of fish and related toxicological mechanisms.
2.Mining of new genes of fish by the methods of comparative proteomics,comparative genomics and bioinformatics.
3. Determination of the function of new fish genes and regulatory factors.



                  2011.2-2013.2 Postdoctoral Scholar,University of Kentucky,USA      
2006.9--2009.12 Ph.D.studies in Food Science, Jiangsu University , China .
2004.9--2007.6 M.S. studies in  Biochemistry and molecular biology. Jiangsu University , 1997.9--2001.6 B.S. studies in Biopharmaceutical Engineering, Nanjing University (1997.9-1999.6) & China Pharmaceutical University(1999.9-2001.6), Nanjing China.Academic Research Experience

Work Experience
2012- Research Associate , Institute of Life Sciences , Jiangsu University
        2011.2-2013.2 Reaseach assistant,University of Kentucky,USA

        2006- 2012 Assistant professor, Institute of Life Sciences , Jiangsu University
2001-2006  Teaching assistant, Institute of Life Sciences , Jiangsu University
2006-2012 assistant professor, Institute of Life Sciences , Jiangsu University


Project and duty
1.  Principal , Analysis and identification of fluoride metabolic associated proteins of Takifugu rubripes, Research Foundation for Talented Scholars,Jiangsu University,No.10JDG087 2010-2012
2.  Principal ,preliminary research on the proteomics and the establishment of protein database of Takifugu rubripes, Natural Science Foundation of the Higher Education Institutions of Jiangsu Province, China.  No.08KJD180008
3. Main participator ,Identification and screening of MicroRNA By computer based on the whole genome of the silkworm Bombyx mori. Natural Science Foundation of the Higher Education Institutions of Jiangsu Province , China . NO. 06KJB180016. 2006-2009
4. Main participator, Research on functional micro-mRNA, micro-peptide and mechanism of interaction between pathogen and host of the Silkworm Bombyx mori. National Program on Key Basic Research Project of China (973 Program) No.2005CB121006. 2005-2010


Papers & Publications

1.Wang X, Mandal AK, Saito H, Pulliam JF, Lee EY, Ke ZJ, Lu J, Ding S, Li L, Shelton BJ, Tucker T, Evers BM, Zhang Z, Shi X*. Arsenic and chromium in drinking water promote tumorigenesis in a mouse colitis-associated colorectal cancer model and the potential mechanism is ROS-mediated Wnt/β-catenin signaling pathway. Toxicol Appl Pharmacol. 262(1), 11-21, 2012

2.Lu J*, Zheng J, Xu Q, Chen K, Zhang C. Adaptive evolution of the vertebrate skeletal muscle sodium channel. Genet Mol Biol. 34(2),323-328,2011

3. Jian Lu* ,Jianzhou Zheng, Haijun Liu ,Jun Li, Huayou Chen ,Keping Chen.Protein profiling analysis of skeletal muscle of a pufferfish, Takifugu rubripes. Mol Biol Rep, 2010,37(5), 2141-2147 . DOI 10.1007/s11033-009-9684-2.
4. Jian Lu*, Jianzhou Zheng, Haijun Liu, Jun Li, Qinggang Xu, Keping Chen.Proteomics analysis of liver samples from puffer fish Takifugu rubripes exposed to excessive fluoride: An insight into molecular response to fluorosis.Journal of Biochemical and Molecular Toxicology, 2010,24 (1): 21 – 28.DOI: 10.1002/jbt.20308.

5.Lu J*, Xu Q, Chen H, Li J,Chen K. Comparative proteomics analysis of midgut samples from takifugu rubripes exposed to excessive fluoride: initial molecular response to fluorosis. Toxicology Mechanisms and Methods.,21(6),444-452,2011


6.Jian Lu*,Huayou Chen; Qinggang Xu; Jianzhou Zheng; Haijun Liu;Jun Li; Keping Chen .Comparative Proteomics of Kidney Samples from Puffer Fish Takifugu rubripes Exposed to Excessive Fluoride: An Insight into Molecular Response to Fluorosis. Toxicology Mechanisms and Methods,2010, 20(6):345-54.DOI:10.3109/15376516.2010.490967.

7. Jian Lu*,Qinggang Xu, Jianzhou Zheng, Haijun Liu, Jun Li, and Keping Chen.Comparative proteomics analysis of cardiac muscle samples from pufferfish Takifugu rubripes exposed to excessive fluoride: initial molecular response to fluorosis.Toxicology Mechanisms and Methods200919(6–7), 468–475.DOI: 10.1080/15376510903170969.

8. Jian Lu*,Haijun Liu,Qin yao,Yong Wang, Keping Chen. An RNA Folding Algorithm Based on Dynamic Weighted Matching. Journal of Biomathetics(Chinese) 200823(4):743-749.
9. Jianzhou Zheng, Jian Lu, Haijun Liu, Jun Li, Keping Chen. Sequence and structural analysis of 4SNc-Tudor domain protein from Takifugu Rubripes. Bioinformation 2009,4(3): 127-131.PMCID: PMC2828898.
10. Hua-you Chen, Xiao-li Tan, Jian Lu,Chun-xia Zhang,Yi Zhang, Sheng-li Yang. Characterization of ATPase activity of class II chaperonin from the hyperthermophilic archaeon Pyrococcus furiosus. Biotechnol Lett 2009,31(11): 1753–1758.DOI: 10.1007/s10529-009-0070-x
11. YongJie Wang, Qin Yao , KePing Chen,Yong Wang,Jian Lu ,Xu Han. Characterization of the genome structure of Bombyx mori densovirus ( China isolate) .Virus Genes ,2007,35:103–108.DOI: 10.1007/s11262-006-0034-3
12. LU Jian,YAO Qin,TANG Xu-dong,XU Qing-gang,CHEN Ke-ping(2004) Purification and Identification of the Genome DNAs of Chinese Species of Bombyxmori.L.Densovirus.Biotechnology(Chinese),14(5).ISSN:1004-311X(2004)05-0035-02
13.Q. Yao,M. W. Li,Y. Wang,W. B. Wang,J. Lu,Y. Dong,K. P. Chen(2003)Screening of molecular markers for NPV resistance in Bombyx mori L. (Lep., Bombycidae).Journal of Applied Entomology,127(3):134-136.
14.Zhao Y, Yao Q, Tang XD, Wang Q, Yin HJ, Hu ZG, Lu J, Chen KP(2007). Cloning and homologic analysis of Tpn I gene in silkworm.Afr. J. Biotechnol. 6(2): 672-676

Jian Lu, Ying dong .Production of L-Alanine by Immobilized Silk Fibroin(2004). Patent( in China ) CN03131658.1